Investigating how physical activity prevents cancers in humans: harnessing ‘big’ data to understand the genomic profile of human cancers that are preventable by physical activity

Project Code

MRCPHS24Ba Campbell

Research Theme

Population Health Sciences

Full Project Description

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How physical activity prevents cancers is unknown. It has been proposed that physical activity may do this by augmenting immune function to reduce the outgrowth of immunogenic cancers. To test this theory, this PhD will analyse cancer genomic and population health datasets to determine whether tumour mutational burden – a biomarker indicative of cancer immunogenicity – is a defining feature of the cancers that are preventable by physical activity.

Lead Supervisor

Dr John Campbell

Lead Supervisor Email

University Affiliation