Project Code MRCIIAR26Ba Reis Project Type Dry lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Bacterial infections affect millions of people worldwide. Current methodologies for bacterial identification and antibiotic susceptibility testing (AST) are time consuming…
Understanding β-lactam antibiotic action and resistance with developments in dynamic structural biology
Project Code MRCIIAR26Ba Tooke Project Type This project combines both wet and dry lab elements. The primary focus will be on wet-lab methods (enzyme purification, biochemical characterisation of enzymes, structural biology) but will feature dry lab approaches (biomolecular simulation). Research…
Exploring Communication Networks in DNA Gyrase: A Pathway to Next-Generation Antibiotic Discovery
Project Code MRCIIAR26Br Oliveira Project Type This is a computational led project using biomolecular simulations, but will include laboratory experiments to test/validate predictions arising from the simulations. Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Bacterial…
Elucidating genetic and immune signatures of severe dengue
Project Code MRCIIAR26Br Rivino Project Type This project is cross-disciplinary and includes both wet and dry lab work (approx 60% wet lab and 40% dry lab). Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Dengue is…
Overcoming β-lactamase-mediated antibiotic resistance by combining biomolecular simulation and experiment
Project Code MRCIIAR26Br Van der Kamp Project Type The project will be a combination of dry and wet; with a focus on dry-lab (computational) activities, but wet-lab based activities are also a key component (enzyme production & purification, enzyme kinetics,…
Sweet disposition: combatting bacterial infections and antimicrobial resistance with designer proteins that target biofilm matrix carbohydrates
Project Code MRCIIAR26Ca Parmeggiani Project Type The project combines dry- and wet-lab elements but aligns more closely with a wet-lab based project considering the costs needed to deliver the work. Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary…
Decoding Lupus: using liquid biopsies to understand autoimmunity
Project Code MRCIIAR26Ex Cano-Gamez Project Type Mixed (50% wet lab, 50% dry lab) Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Lupus is a serious autoimmune disease where the immune system attacks the body’s own cells.…
Understanding and supporting psychological trauma related to the experience and treatment of eating disorders
Project Code MRCNMH26Ba Atkinson Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Eating disorders (EDs) can be linked to early trauma (physical and psychological). However the experience of having an ED – and going…
Multi-method exploration into psychosocial contributors to pain across the lifespan
Project Code MRCNMH26Ba Barry Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Chronic pain is the costliest health problem that exists. Our understanding of the psychological and social processes that explain why some people…
Can young people’s cognitive style explain associations between social media use and mental health?
Project Code MRCNMH26Ba Button Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary In public discourse, social media is often claimed to be bad for young people’s mental health. This simple view is not supported…