Boosting the Brain Cell Recycling System: Peptide Activation of TFEB in Neurodegeneration

Project Code NMH27Ba Mason Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary Many neurodegenerative diseases, including Parkinson’s disease, involve failure of the cell’s waste-clearance system, allowing damaged proteins and organelles to accumulate. TFEB is a…

Anxiety-Related Attention Bias in Everyday Situations: Mechanisms and VR-Based Modification

Project Code NMH27Ba Voinescu Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Anxiety can distort how we pay attention, making us overly focused on potential threats and less able to respond flexibly to what…

Combining epigenetics and neuroimaging to predict mental health traits across child development

Project Code NMH27Ba Walton Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Epigenetic and structural brain alterations have been separately linked to neurodevelopmental and psychiatric conditions, but little is known about their combined impact…

Can Virtual Reality (VR) embodiment experiences be used as part of treatment for eating disorders?

Project Code NMH27Br Bould Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Current treatments for eating disorders work for less than half of those affected, so it is vital to develop novel treatments. Virtual…

Decoding Early Brain and Movement Signals to Predict Outcomes after Birth Asphyxia

Project Code NMH27Br Chakkarapani Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Birth asphyxia occurs when a baby is deprived of oxygen around birth, causing brain injury, disability or death. This project will study…

Molecular basis of CASK mutations and their role in neural development

Project Code NMH27Br Corey Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary This interdisciplinary PhD project will investigate how disease-causing mutations alter the structure and function of CASK, a key protein required for synaptic development,…

Mapping the biology of complex brain disorders: uncovering molecular pathways and identifying potential drug targets

Project Code NMH27Br D’Andrea Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Developing medicines to treat brain disorders such as schizophrenia has proven extremely difficult, with many new drugs failing in late-stage clinical trials.…

Developing brain-activity based non-invasive stimulation techniques for movement disorders

Project Code NMH27Br Fischer Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Parkinson’s disease and dystonia can severely affect movement, and existing treatments do not work well for everyone. This PhD project will develop…