Project Code NMH27Br Sharp Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary This interdisciplinary project provides training in global mental health and advanced epidemiological/statistical methods. Using data from two large cohorts in the Philippines…
Shared Genetic Architecture of Neuropsychiatric Disorders and Novel Brain Biomarkers: Towards Understanding Biological Processes
Project Code NMH27Ca Caseras Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary The field of imaging genetics has had limited success identifying shared common risk variants between mental disorders and brain phenotypes, this being…
Mapping the Developing Brain: Linking Structure and Function through Imaging
Project Code NMH27Ca Cercignani Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary This PhD project explores how young children’s brain develops during the first five years of life and how this shapes thinking, language, and…
Finding the Earliest Signs of Psychosis: Studying Young People at High Genetic Risk
Project Code NMH27Ca Chawner Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Why do some young people develop psychosis while others do not? This project will investigate the developmental origins of psychosis in young…
Gene-diet interaction and psychiatric risk: A study based of FADS 2 and dietary polyunsaturated fatty acids (PUFAs)
Project Code NMH27Ca Harwood Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary Mental Health: nature or nurture? For psychiatric disorders the answer is both, but to explain how, we need to know the molecular mechanisms?…
Unravelling the Physiological Drivers of Sleep-Dependent Glymphatic Flow in Alzheimer’s Disease using Advanced MRI
Project Code NMH27Ca Murphy Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary Poor sleep is linked to increased future dementia risk. The SleepBoost study is a £4.3m multi-centre investigation into this link and aims to…
Medication adherence in young people with first episode psychosis: a longitudinal mixed-methods biopsychosocial study of decision making
Project Code NMH27Ca Roberts Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Antipsychotic medication can reduce or resolve psychotic symptoms and help prevent relapse, but adherence remains challenging, particularly for young people with first…
From Multi-OMICs to mechanism: understanding the links between protein turnover and therapy resistance in glioblastoma stem cells
Project Code NMH27Ca Siebzehnrubl Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary How do glioblastoma stem cells evade therapy and drive tumour recurrence? This project will address this question by investigating how FGF2-FGFR1 signalling regulates…
Chronic pain, sensory hypersensitivity and neurodiversity: why are they linked?
Project Code NMH27Ca Sumner Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Chronic pain conditions such as fibromyalgia, dysmenorrhea and back pain affect millions of people and severely disrupt daily life. An interesting but…
Pain as neurobiological surprise: Using human brain imaging and animal studies to advance new concepts in persistent pain.
Project Code NMH27Ca Tackley Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary We experience surprise when our best guess about the immediate future turns out to be wrong. This can be dangerous: it might mean…