Novel morphological markers of congenital heart disease: from computational modelling to population data

Project Code MRCPHS25Br Biglino Research Theme Population Health Sciences Project Summary Download Summary Congenital heart disease (CHD) affects 1/110 births, causes 220,000 deaths/year and affects 13+ million worldwide. The aetiology of CHD is complex, with evidence of both genetic and…

How safe are antiseizure medications in pregnancy for conditions other than epilepsy?

Project Code MRCPHS25Ba McGrogan Research Theme Population Health Sciences Project Summary Download Summary Did you know that only 5% of medicines licensed in the UK have sufficient evidence about their safety in pregnancy? Women may be advised not to use…

Causal inference tools to study vaccines using real-world data: how can we make better use of negative control outcomes?

Project Code MRCPHS25Ba McDonald Research Theme Population Health Sciences Project Summary Download Summary “Vaccination saves lives! Observational vaccine studies are important to assess real-world effectiveness and safety, but people who receive vaccines differ from those who do not, so confounding…

Parental transmission of substance use: exploring mechanisms and informing intervention

Project Code MRCPHS25Ba Hines Research Theme Population Health Sciences Project Summary Download Summary Reducing substance use is a key goal within public health. Recent work has shown that a strong predictor of adolescent substance use is the substance use of…

An investigation of the factors that influence post-disaster mental health in a Brazilian birth cohort study

Project Code MRCPHS25Ba Halligan Research Theme Population Health Sciences Project Summary Download Summary Exposure to traumatic events like disasters is a major risk factor for poor mental health. However, understanding of the pre-existing factors that contribute to better or worse…

Genetic predisposition to accelerated ageing: targeting telomeres using sex hormone supplementation in Idiopathic Pulmonary Fibrosis

Project Code MRCPHS24Ex Scotton Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Lung fibrosis is a devastating disease which causes 1% of…

Understanding and addressing inequalities in the cancer diagnostic pathway for people with anxiety and/or depression

Project Code MRCPHS24Ex Price Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary This multi-disciplinary PhD builds on Exeter and Cardiff research aiming…

Using modelling approaches to reduce inequality in physical activity interventions

Project Code MRCPHS24Ex Kelson Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Physical activity promotes health & wellbeing. Policy makers seek interventions…

Investigating the penetrance of cancer susceptibility genes in a population cohort and the influences of family history and rare and common genetic modifiers

Project Code MRCPHS24Ex Jackson Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Offering genetic testing only to those with a family history…