Project Code
MRCIIAR25Ca Stanton
Research Theme
Infection, Immunity, Antimicrobial Resistance and Repair
Project Summary Download
Summary
Neutralizing antibodies are key to preventing transmission of SARS-CoV-2, however the virus can rapidly mutate to avoid these. Furthermore, once infected, neutralizing antibodies cannot access intracellular virus. Therefore, antibodies that recognise cell-associated virus are critical. However, current vaccines fail to induce these. We will investigate how this activity can be induced, as the basis for next-generation and variant-resistant coronavirus vaccines.
Lead Supervisor
Professor Richard Stanton
Lead Supervisor Email
stantonrj@cardiff.ac.uk
University Affiliation
Cardiff