Calcium signalling in In-Vitro Fertilization: developing a non-invasive diagnostic tool

Project Code

MRCPHS25Ca Kaouri

Research Theme

Population Health Sciences

Project Summary Download

Summary

In-Vitro Fertilization is the primary treatment of infertility, with ~2.5 million cycles performed annually. Success rates are, however, declining partly due to waiting 5 days to select the best embryo to transfer to the woman. A rapid (day 1) indicator of embryo viability will be developed though sophisticated mathematical modelling, and AI, informed by the analysis of experimental data on calcium signalling in fertilising eggs and their movements. The proposed diagnostic tool has the potential to significantly improve IVF treatments

Lead Supervisor

Dr Katerina Kaouri

Lead Supervisor Email

kaourik@cardiff.ac.uk

University Affiliation

Cardiff