Project Code MRCIIAR25Br Mann Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary This project addresses the ongoing challenge posed by HIV-1, a virus infecting approximately 38 million people globally, with Subtype C (C-HIV) as the most…
Developing new weapons to fight drug-resistant superbugs – targeting lipoteichoic acid biosynthesis
Project Code MRCIIAR25Br Laabei Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Antimicrobial resistance (AMR) has been described as the silent pandemic, fuelled in part by insufficient antibiotic development. We have identified novel small molecules that…
Emerging co-resistance to first and second line antibiotics in urinary pathogens and implications for the control of urosepsis.
Project Code MRCIIAR25Br Avison Research Theme Infection, Immunity, Antimicrobial Resistance and Repai Project Summary Download Summary Reducing antibiotic resistance (ABR) among urosepsis pathogens – derived from urinary tract infection (UTI) via pyelonephritis – is central to the UKs ABR-reduction strategy.…
Airborne transmission of pathogens: defining microbial and environmental factors affecting survival in aerosols.
Project Code MRCIIAR25Ba Preston Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Numerous bacteria transmit between hosts via the air, representing a key step in the pathogen lifecycle. However, we know little about the microbial and…
Tackling Antimicrobial Resistance with Targeted Covalent Macrocycles
Project Code MRCIIAR25Ba Lovell Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Infections with drug-resistant bacteria are major threats to human health. Discovering novel druggable targets for antimicrobial development is a pivotal task to guarantee effective…
Using AI to understand defence and counter-defence systems between bacteria and phage
Project Code MRCIIAR25Ba Iqbal Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Bacteria have been engaged in a war with the viruses that predate on them (“phage”) for millions of years, both sides developing defence/counter-defence systems.…
Environmental and genetic determinants of transmission by a parasitic nematode
Project Code MRCIIAR25Ba Hunt Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary The parasitic nematode Strongyloides infects >600 million people and is transmitted between hosts through a larval stage in the soil. We know little about…
The Contribution of Mitochondrial Dysfunction to Alzheimer’s disease
Opening date: Tuesday 2nd April 2024
Closing date: Wednesday 1st May 2024 at 5pm
Project Code MRC24NMHCa
Closing date: Wednesday 1st May 2024 at 5pm
Project Code MRC24NMHCa
Jessica Foley: A Hundred Happy Birthdays: Music and Ageing at Green Man Festival
Jessica Foley, BioMed1 student in cohort 5, has written a fantastic blog on her experience at Green Man this year. Below is an excerpt, and you can read the whole post on Bristol’s Doctoral College Blog. “My PhD work focuses…
Combating Cancer with Data Science: Deep Learning of Histological Images for the Detection of Lymph Node Metastases
Project Code MRCIIAR24Ca Farnell Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Lymph nodes are a common site for the spread of cancer. The student will learn state-of-the-art techniques in Data Science involving Deep Learning to…