Infection, Immunity, Antimicrobial Resistance and Repair
Full Project Description
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Tumour infiltrating lymphocytes (TILs) are lymphocytes that can be found within solid tumours. Some TILs are cancer-specific and if expanded can be used for immunotherapy. However, not all patients respond to TIL therapy. We aim to elucidate the impact that cancer cells might have on TIL function. Using 3D culture imaging, we reveal the interaction between cancer cells and TILs and examine possible factors that impact the way in which cancer cells respond to TILs.
Dr Nobue Itasaki
Lead Supervisor Email