Investigating the biological intersection between Alzheimer’s risk genetics and cognitive reserve

Project Code

MRCNMH24Ba Lancaster

Research Theme

Neuroscience and Mental Health

Full Project Description

Please download the below document for a full project description and to see the full supervisory team.


The genetic architecture for Alzheimer’s disease (AD) overlaps substantially with the genetics variants that influence individual differences in intelligence and cognition, supporting a hypothesis that ‘cognitive reserve’ is protective against AD. This project will employ an array of bioinformatic tools to identify how these processes overlap and how it manifests at a neurobiological level and across the lifespan.

Lead Supervisor

Dr Tom Lancaster

Lead Supervisor Email

University Affiliation