Project Code MRCIIAR26Ba Reis Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Bacterial infections affect millions of people worldwide. Current methodologies for bacterial identification and antibiotic susceptibility testing (AST) are time consuming…
Understanding β-lactam antibiotic action and resistance with developments in dynamic structural biology
Project Code MRCIIAR26Ba Tooke Project Type This project combines both wet and dry lab elements. The primary focus will be on wet-lab methods (enzyme purification, biochemical characterisation of enzymes, structural biology) but will feature dry lab approaches (biomolecular simulation). Research…
Tuning the Innervation Capacity of Regenerative Biomaterials
Project Code MRCIIAR26Br Armstrong Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Biomaterials can be used to regenerate diseased or damaged tissues. Substantial progress has been made in our understanding of the…
Tackling tick-borne pathogenic bacteria through SLiMs
Project Code MRCIIAR26Br Cadby Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary In this PhD you will use molecular and protein biochemistry approaches to understand how Short Linear Motif (SLiM) containing virulence…
Artificial intelligence to identify antifungal susceptibility in the clinical diagnostic laboratory
Project Code MRCIIAR26Br Dowsey Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Fungal infections have become a major and growing global health crisis, causing an estimated 3.8 million deaths each year particularly…
Microplastics, big problems: dissecting effects on the immune system and skeletal repair
Project Code MRCIIAR26Br Hammond Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary There is a growing awareness that micro- and nanoplastics, which are increasingly prevalent in our environment, pose risks to human…
Bridging the Gap: Improving Access to Care for people at Risk of Type 1 Diabetes
Project Code MRCIIAR26Br Long Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary A paradigm shift is underway in type 1 diabetes (T1D) treatment. For over a century, T1D has been managed, but…
Hidden codes: Genetic Determinants of HIV-1 Fitness and Immune Recognition
Project Code MRCIIAR26Br Mann Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary This project addresses the ongoing challenge posed by HIV-1, a virus infecting approximately 38 million people globally, with Subtype C…
Exploring Communication Networks in DNA Gyrase: A Pathway to Next-Generation Antibiotic Discovery
Project Code MRCIIAR26Br Oliveira Project Type This is a computational led project using biomolecular simulations, but will include laboratory experiments to test/validate predictions arising from the simulations. Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Bacterial…
Elucidating genetic and immune signatures of severe dengue
Project Code MRCIIAR26Br Rivino Project Type This project is cross-disciplinary and includes both wet and dry lab work (approx 60% wet lab and 40% dry lab). Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Dengue is…