Single-shot diagnosis of ion channel dysfunction in neurological disease from data assimilation of cell membrane dynamics

Project Code

MRCNMH24Ba Nogaret

Research Theme

Neuroscience and Mental Health

Full Project Description

Please download the below document for a full project description and to see the full supervisory team.


Ion channel mutations play an increasingly recognised role in Epilepsy and Alzheimer’s disease. This project will apply inverse computational methods to infer ion channel dysfunction from time series analysis of electrophysiological recordings. The link between anomalous electrical activity in the brain and channelopathies that will be established by this studentship will identify new therapeutic targets for neurological disease.

Lead Supervisor

Professor Alain Nogaret

Lead Supervisor Email

University Affiliation