Airborne transmission of pathogens: defining microbial and environmental factors affecting survival in aerosols.

Project Code MRCIIAR25Ba Preston  Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Numerous bacteria transmit between hosts via the air, representing a key step in the pathogen lifecycle. However, we know little about the microbial and…

Tackling Antimicrobial Resistance with Targeted Covalent Macrocycles

Project Code MRCIIAR25Ba Lovell Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Infections with drug-resistant bacteria are major threats to human health. Discovering novel druggable targets for antimicrobial development is a pivotal task to guarantee effective…

Using AI to understand defence and counter-defence systems between bacteria and phage

Project Code MRCIIAR25Ba Iqbal Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Bacteria have been engaged in a war with the viruses that predate on them (“phage”) for millions of years, both sides developing defence/counter-defence systems.…

Environmental and genetic determinants of transmission by a parasitic nematode

Project Code MRCIIAR25Ba Hunt  Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary The parasitic nematode Strongyloides infects >600 million people and is transmitted between hosts through a larval stage in the soil. We know little about…

Theranostics and Multimodal Imaging with Near-Infrared Emitting Peptide Nucleic Acids

Project Code MRCIIAR24Ba Pascu Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary The cancer incidence number is expected to…

Developing new weapons to fight drug-resistant superbugs – targeting lipoteichoic acid biosynthesis

Project Code MRCIIAR24Ba Laabei Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Antimicrobial resistance (AMR) is a major threat…

Genetic signatures of parasitism in clinically important strains of a gastrointestinal parasite

Project Code MRCIIAR24Ba Hunt Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Strongyloides stercoralis is an intestinal parasite infecting…

Evolution of antimicrobial resistance in bacterial microbiomes

Project Code MRCIIAR24Ba Jones Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Biocides are broad spectrum antimicrobial agents used…

How are changing environments on our farms driving antifungal resistance in clinical fungal pathogens?

Project Code MRCIIAR24Ba Brown Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Fungal pathogens cause deadly human infections, destroy…