Using genetics to understand neurodevelopmental outcomes in children born with cleft from a clinical birth cohort

Project Code MRCNMH26Br Stergiakouli Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary This project will provide in-depth training in genetic epidemiology, neurodevelopmental disorders, cohort studies and cleft. The student will have the opportunity to…

Unlocking the causes of eating disorders: investigating risk factors across development

Project Code MRCNMH25Ca Chawner Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Tackling eating disorders is of growing importance in society, with increasing numbers of children and young people referred to eating disorder services.…

How ADHD affects curiosity and curiosity-based learning

Project Code MRCNMH26Ca Gruber Project Type The project will combine behavioural and neuroimaging studies (in particular, functional Magnetic Resonance Imaging, fMRI) in human participants. Research Theme Neuroscience and Mental Health Project Summary Download Summary This PhD project explores how curiosity…

Novel area-modulation stimuli for identifying changes in visual field sensitivity in Age-related Macular Degeneration (AMD)

Project Code MRCNMH26Ca Redmond Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Age-related macular degeneration (AMD) is one of the world’s leading causes of sight loss. Traditional measures of vision in AMD are of…

Communication Breakdown: Using human assembloid models to understand disruption of neuron-glia interactions in ALS.

Project Code MRCNMH26Ex Bhinge Project Type Primarily wet-lab with a strong computational component. Research Theme Neuroscience and Mental Health Project Summary Download Summary ALS is a devastating neurological disease with no cure, and we urgently need new ways to understand…

Architects of the Genome: Using genomic technologies to elucidate the role of CTCF in neurodevelopmental disorders

Project Code MRCNMH26Ex Flynn Project Type The project is primarily wet-lab based, with a dry-lab component in Years 2 and 3. Research Theme Neuroscience and Mental Health Project Summary Download Summary Genetic variants in the CTCF gene, which encodes a…

Epigenetic profiling in Parkinson’s disease: novel mechanisms and drug targets

Project Code MRCNMH26Ex Migdalska-Richards Project Type A particular strength of this project is that it combines both wet-lab work (microRNA profiling, cell culturing and transfection) and bioinformatics, allowing the student to acquire a valuable combination of skills that will be…

Molecular signatures of sex differences in the human brain

Project Code MRCNMH26Ex Mill Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Why do males and females show different risks for brain disorders like schizophrenia, depression, autism and Alzheimer’s? This project explores how sex…

Ketamine Use Disorder: Exploring Psychological and Neurological Mechanisms

Project Code MRCNMH26Ex Morgan Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Ketamine use disorder is the fastest growing addiction in the UK, with ~ 300% increase in people seeking treatment over the past…