Project Code MRCIIAR25Ex Padfield Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Recent studies have shown that levels of antimicrobial resistance (AMR) increase at higher environmental temperatures, but we have limited understanding of the mechanisms causing…
Investigating the impact of epigenetic modifiers, a new treatment for cancer, on fungal pathogens
Project Code MRCIIAR25Ex Neutzmann Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Fungal pathogens threaten our health and kill over a million patients worldwide. In this project, we will deploy cutting-edge epigenetics research and medical microbiology…
Uncovering new genetic mechanisms of beta-cell autoimmunity to better understand type 1 diabetes
Project Code MRCIIAR25Ex Johnson Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary This project uses a unique collection of samples from people with diabetes to address a fundamental question: What are the genetic mechanisms underpinning beta-cell…
Developing new therapies against the most dangerous antibiotic resistant bacteria
Project Code MRCIIAR25Ex Harmer Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Antimicrobial resistance is an increasing societal issue, contributing to ~5,000,000 deaths in 2019. The highest priority bacteria are the ESKAPE pathogens that account for…
Investigating oxygenated sterols and lipids in tuberculosis (TB) infection: human’s friend and pathogen’s foe?
Project Code MRCIIAR25Ex Borah Slater Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary “Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is a devastating infectious disease causing over one million human deaths every year. We urgently need…
Virtual Reality Toolkit for Diabetes
Project Code MRCPHS24Ex Vaughan Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary A novel Virtual Reality (VR) toolkit for diabetes will be…
Genetic predisposition to accelerated ageing: targeting telomeres using sex hormone supplementation in Idiopathic Pulmonary Fibrosis
Project Code MRCPHS24Ex Scotton Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Lung fibrosis is a devastating disease which causes 1% of…
Understanding and addressing inequalities in the cancer diagnostic pathway for people with anxiety and/or depression
Project Code MRCPHS24Ex Price Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary This multi-disciplinary PhD builds on Exeter and Cardiff research aiming…
Using modelling approaches to reduce inequality in physical activity interventions
Project Code MRCPHS24Ex Kelson Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Physical activity promotes health & wellbeing. Policy makers seek interventions…
Investigating the penetrance of cancer susceptibility genes in a population cohort and the influences of family history and rare and common genetic modifiers
Project Code MRCPHS24Ex Jackson Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Offering genetic testing only to those with a family history…