Project Code MRCNMH26Ex Witton Project Type Wet lab Research Theme Population Health Science Project Summary Download Summary Microglia are the brain’s resident immune cells. The latest research suggests that, alongside conventional molecular signals, microglia function is also influenced by certain…
Unveiling the Journey from Action Potential to Behaviour: Exploring Dopamine and Acetylcholine in Health and Disease
Project Code MRCNMH26Ex Zhang Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary How does the brain’s dopamine system drive learning, memory, and motivation? And what goes wrong in diseases like Parkinson’s? This project will…
Under pressure: Investigating the role of breast density and tissue mechanics in breast cancer development
Project Code MRCPHS26Br Lloyd-Lewis Project Type Wet lab Research Theme Population Health Science Project Summary Download Summary A high breast mammographic density is a major risk factor for breast cancer, yet the underlying molecular mechanisms remain unclear. In this interdisciplinary…
Determining jaw joint mechanics by characterising shape, genetics and material properties in wild type and mutant zebrafish
Project Code MRCPHS26Br Rayfield Project Type Wet lab Research Theme Population Health Science Project Summary Download Summary This project explores how joints respond to mechanical forces throughout life, using zebrafish as a model to understand joint ageing and degeneration. By…
Disrupted Mechanical Signalling at the Golgi apparatus as a Driver of Osteoarthritis Progression
Project Code MRCPHS26Br Stevenson Project Type Wet lab Research Theme Population Health Science Project Summary Download Summary Nearly 8% of the global population is living with osteoarthritis. The mechanisms of disease are poorly understood, however a major risk factor is…
Modelling and Communicating Avian Influenza Spillover at the Human–Wild Bird Interface: A One Health Approach
Project Code MRCPHS26Br Thomas Project Type Dry and wet lab, including field work. This is an interdisciplinary project.Predominantly the student will be dry lab to conduct modelling and co-production aspects. The student can participate in data collection in the field,…
Phenotypic and epigenetic analyses of Foetal Alcohol Spectrum Disorder (FASD) in the zebrafish model and human patients
Project Code MRCPHS26Ex Kudoh Project Type Wet lab Research Theme Population Health Science Project Summary Download Summary Foetal Alcohol Spectrum Disorder (FASD) occurs via alcohol consumption in pregnancy with 1-5% frequency in humans, causing distinctive facial features alongside brain development…
Regenerating insulin cells by using new designer biologics to fine-tune neural signals
Project Code MRCPHS26Ex Yang Project Type Wet lab Research Theme Population Health Science Project Summary Download Summary A hallmark of type 1 diabetes is elevated blood glucose levels caused by autoimmune destruction of the insulin-producing beta-cells. The existence of remnant…