Project Code NMH27Br Hodge Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary With ageing your 24-hour clock (circadian rhythms) and sleep get weaker. These symptoms are more pronounced in Alzheimer’s with poor rhythms and…
Linking neuronal function to mental health: How genetic risk factors impair cognitive flexibility and neural plasticity in schizophrenia
Project Code NMH27Br Mellor Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Genetic risk factors for schizophrenia are clustered around genes that regulate synaptic function and adaptation, pointing to underlying biological processes whose disruption…
Quietly healing trauma: enhancing emotional processing during sleep with targeted memory reactivation
Project Code NMH27Br Purple Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Why do some people recover from trauma while others develop posttraumatic stress disorder (PTSD)? Sleep is known to play an essential role…
Quantifying the impact of heatwaves on cognition, neuroanatomy, and mitochondrial function
Project Code NMH27Br Siviter Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Climate change is increasing the frequency and severity of heatwaves. In the UK, homes and essential infrastructure are not adequately prepared for…
Mapping the Developing Brain: Linking Structure and Function through Imaging
Project Code NMH27Ca Cercignani Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary This PhD project explores how young children’s brain develops during the first five years of life and how this shapes thinking, language, and…
Gene-diet interaction and psychiatric risk: A study based of FADS 2 and dietary polyunsaturated fatty acids (PUFAs)
Project Code NMH27Ca Harwood Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary Mental Health: nature or nurture? For psychiatric disorders the answer is both, but to explain how, we need to know the molecular mechanisms?…
Towards Precision Psychiatry: Early Detection and Intervention in Schizophrenia
Project Code NMH27Ca Heurich Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Schizophrenia affects around 1% of the population and remains one of the most challenging mental health disorders to predict and treat. Increasing…
Investigating placental function and fetal programming in Prader–Willi Syndrome
Project Code NMH27Ca Isles Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary By bringing together transcriptomics and cutting edge imaging, and dataanalysis techniques, this PhD project aims to examine how abnormalitiesin placental function leads…
Power Failure: Why Neurons Die in Huntington’s Disease
Project Code NMH27Ca Massey Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Huntington’s disease is an inherited brain disorder that causes progressive movement, cognitive and sleep problems, yet there is still no effective treatment.…
Unravelling the Physiological Drivers of Sleep-Dependent Glymphatic Flow in Alzheimer’s Disease using Advanced MRI
Project Code NMH27Ca Murphy Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary Poor sleep is linked to increased future dementia risk. The SleepBoost study is a £4.3m multi-centre investigation into this link and aims to…