Defining CD200 Function and the Therapeutic Potential of Targeting the CD200 immune checkpoint in Prostate Cancer

Project Code IIAR27Ca Pearson Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Prostate cancer remains a leading cause of cancer mortality, particularly in metastatic disease where treatment options are limited. This PhD project…

Optimising immune responses against emerging viruses

Project Code IIAR27Ca Stanton Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Worldwide, viruses that transmit to humans from biting insects account for ~17% of infectious diseases and ~700,000 deaths/yr, with ~4 billion…

Cracking the Host-Pathogen Metabolic Code in Tuberculosis: Discovering New Therapeutic Strategies

Project Code IIAR27Ex Borah Slater Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Tuberculosis (TB) remains one of the world’s leading infectious killers, with the urgent need for new treatments. This exciting PhD…

Phage Power: Optimising Treatments for Bacterial Co-Infections

Project Code IIAR27Ex Castledine Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary As antibiotic resistance threatens modern medicine, phage therapy is emerging as a powerful new weapon against bacterial infections. These naturally occurring…

How does temperature shape selection for resistance across different antibiotics, strains, and species

Project Code IIAR27Ex Padfield Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Climate warming is linked to rising antimicrobial resistance (AMR), but the biological mechanisms remain poorly understood. This project asks how temperature…

Developing CRISPR-Cas antimicrobials to tackle antibiotic resistance spread in Klebsiella pneumoniae

Project Code IIAR27Ex van Houte Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Antimicrobial resistance (AMR) poses a major threat to human health, which is for a large part driven by plasmids (mobile…

Bacterial pathogen evolution during antibiotic-phage combination treatment

Project Code IIAR27Ex Westra Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Antimicrobial resistance is a major threat to modern medicine, and bacteriophage therapy is a promising route to treat drug-resistant infections. Yet…

Stress reactivity and mental health in young people; how do we measure it, and can we fix it when it goes wrong?

Project Code NMH27Ba Jacobsen Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary How a person reacts to stressful things in everyday life is known as ‘stress reactivity’. This includes how a person reacts in…

Beyond Pain Intensity: Ecological Measurement and Neurostimulation of Pain-Related Motor Interference

Project Code NMH27Ba Khatibi Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary This project will develop and validate an ecologically meaningful measure of pain-related interference with motor function. Rather than relying on simple laboratory tasks…