Using a new translational in vivo model to understand the neurobiology underlying ADHD subtypes

Project Code

MRCNMH24Ca Davies

Research Theme

Neuroscience and Mental Health

Full Project Description

Please download the below document for a full project description and to see the full supervisory team.

Summary

In mice and humans loss-of-function of the steroid sulfatase (STS) enzyme results in inattention but enhanced motor response inhibition; we aim to understand the neurobiology underlying this dissociation using a new mouse model. The project will develop behavioural neuroscience research skills, will have direct clinical relevance to X-linked ichthyosis (STS deficiency), and will signpost mechanisms associated with Attention Deficit Hyperactivity Disorder subtypes.

Lead Supervisor

Dr William Davies

Lead Supervisor Email

daviesw4@cardiff.ac.uk

University Affiliation

Cardiff