Using a new translational in vivo model to understand the neurobiology underlying ADHD subtypes

Project Code

MRCNMH24Ca Davies

Research Theme

Neuroscience and Mental Health

Full Project Description

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In mice and humans loss-of-function of the steroid sulfatase (STS) enzyme results in inattention but enhanced motor response inhibition; we aim to understand the neurobiology underlying this dissociation using a new mouse model. The project will develop behavioural neuroscience research skills, will have direct clinical relevance to X-linked ichthyosis (STS deficiency), and will signpost mechanisms associated with Attention Deficit Hyperactivity Disorder subtypes.

Lead Supervisor

Dr William Davies

Lead Supervisor Email

University Affiliation