Infection, Immunity, Antimicrobial Resistance and Repair
Full Project Description
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The induction and persistence of effective antigen(Ag)-specific memory T-cell responses is required to bestow long-term protection against infectious diseases, and hence is critical to vaccine development. However, evolution of such T-cell responses can lead to impaired secondary (e.g. to influenza virus) or aberrant (e.g. to Dengue virus) responses. The student will examine age and evolution of several Ag-specific T-cells responses at steady state and over time.
Dr Kristin Ladell
Lead Supervisor Email