Genetics underpinnings of antibiotics-phage synergy

Project Code

MRCIIAR24Ex Westra

Research Theme

Infection, Immunity, Antimicrobial Resistance and Repair

Full Project Description

Please download the below document for a full project description and to see the full supervisory team.


Antimicrobial resistance (AMR) poses a threat to our healthcare system. Phage therapy (PT), the use of lytic phages to treat bacterial infections can be an effective last-resort treatment, but efficacies remain hard to predict. PT is typically applied in combination with conventional antibiotics. This project aims to examine how and why the efficacy of PT-antibiotics combination therapy depends on the type(s) of phage and the type and dose of antibiotics.

Lead Supervisor

Professor Edze Westra

Lead Supervisor Email

University Affiliation