Cell communication in gastric cancer

Project Code

MRCIIAR24Ex Scholpp

Research Theme

Infection, Immunity, Antimicrobial Resistance and Repair

Full Project Description

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Cells communicate with a language of chemical signals to orchestrate cell behaviour at a distance. We have shown that signalling protrusions, namely cytonemes, transport Wnt signals, between distant cells. In gastric cancer, we observed an increased cytoneme network directly linked to tumour growth. This project will use cancer cell assays and xenograft technology to study the importance of cytoneme-mediated, paracrine Wnt signalling transport in 3D.

Lead Supervisor

Professor Steffen Scholpp

Lead Supervisor Email


University Affiliation