Investigating the neurobiological mechanisms underlying apathy in Parkinson’s disease

Project Code

MRCNMH24Br Robinson

Research Theme

Neuroscience and Mental Health

Full Project Description

Please download the below document for a full project description and to see the full supervisory team.

Summary

Apathy is a debilitating and highly prevalent symptom in people with Parkinson’s disease. It is often refractory to conventional dopaminergic therapy and is associated with poorer health-related quality of life. No specific treatment for apathy exists, partly as little is known about its neurobiology. Using clinical data and preclinical in vivo methods, this project aims to investigate the neurobiology of apathy and explore the mechanisms of promising therapeutics.

Lead Supervisor

Professor Emma Robinson

Lead Supervisor Email

pmesjr@bristol.ac.uk

University Affiliation

Bristol