Project Code
MRCPHS25Ex Hawkes
Research Theme
Population Health Sciences
Project Summary Download
Summary
A person’s health is influenced by their socioeconomic status, smoking and other behavioural and environmental factors, as well as their genetic make-up. Some genetic variants directly affect protein sequence, while others act as switches that turn protein production on and off, depending on cell and life stage. But both, alone and combined, can affect a person’s health. In this project, you will use recently released data on 3,000 proteins from 50,000 participants with their full genetic sequence to investigate how environmental and genetic effects combine to affect an individual’s metabolic disease risk profile, in particular diabetes and obesity.
Lead Supervisor
Dr Gareth Hawkes
Lead Supervisor Email
g.hawkes2@exeter.ac.uk
University Affiliation
Exeter