Once bitten, twice shy: the impact of helminth infection on viral immunity

Project Code

MRCIIAR24Ca Smith

Research Theme

Infection, Immunity, Antimicrobial Resistance and Repair

Full Project Description

Please download the below document for a full project description and to see the full supervisory team.

Summary

Although studies suggest that soil-transmitted helminth (STH)-infections influence human papillomavirus (HPV) infection (once bitten), it is not known how STH infection influence how they then deal with repeated exposure to the virus (twice shy). Using established in vitro assays, pre-clinical models and human samples, the aim of this project is to determine the processes by which STH influence immunity to pathogenic viral infections.

Lead Supervisor

Dr Katherine Smith

Lead Supervisor Email

smithk28@cardiff.ac.uk

University Affiliation

Cardiff