Fighting antimicrobial resistance by stopping bacterial cell division

Project Code


Research Theme

Infection, Immunity, Antimicrobial Resistance and Repair

Full Project Description

Please download the below document for a full project description and to see the full supervisory team.


The continuing rise of antimicrobial resistance has led to the failure of antibiotics to treat common infections. This project proposes to develop novel antimicrobials that target bacterial cell division, a crucial step for bacterial replication and survival. We will combine our expertise in medicinal chemistry and microbiology to design molecules that, acting like “Trojan horses”, cross the bacterial cell envelope and once inside become toxic and kill the bacteria.

Lead Supervisor

Dr Michaela Serpi

Lead Supervisor Email

University Affiliation