Project Code MRCNMH25Ca Slator Research Theme Neuroscience & Mental Health Project Summary Download Summary This project will develop advanced machine learning methods for medical imaging to non-invasively characterise brain tissue structure and function. The project focuses on quantitative MRI, which…
Enabling continuous, personalised stress quantification and management with a wearable system
Project Code MRCNMH25Ca Pham Research Theme Neuroscience & Mental Health Project Summary Download Summary Nine in ten adults in the UK suffer from high or extreme stress in 2023. Stress-related disorders and burnout cost the UK economy more than £28…
Developing a new therapeutic strategy for brain cancers: getting therapeutics directly to the tumour
Project Code MRCNMH25Ca Newland Research Theme Neuroscience & Mental Health Project Summary Download Summary Some brain cancers cannot be surgically removed, and many potent therapeutics cannot reach the tumour site. This project aims to overcome these hurdles by utilizing a…
Unravelling the Pharmacological Activation of PINK1, a Protein Kinase Mutated in Parkinson’s Disease
Project Code MRCNMH25Ca Mehellou Research Theme Neuroscience & Mental Health Project Summary Download Summary “Parkinson’s disease (PD) is the second most common neurological disease in the world. Current PD therapies and medical interventions are limited to addressing the symptoms of…
Using MRI, MEG, and machine learning to better classify severe mental illness
Project Code MRCNMH25Ca McNabb Research Theme Neuroscience & Mental Health Project Summary Download Summary Clinical diagnoses of severe mental illnesses currently rely solely on symptom report and poorly predict long-term outcomes. This PhD project aims to integrate information from brain…
Using a new translational in vivo model to understand the neurobiology underlying ADHD subtypes
Project Code MRCNMH25Ca Davies Research Theme Neuroscience & Mental Health Project Summary Download Summary In mice and humans loss-of-function of the steroid sulfatase (STS) enzyme results in inattention but enhanced motor response inhibition; we aim to understand the neurobiology underlying…
Unlocking the causes of eating disorders: investigating risk factors across development
Project Code MRCNMH25Ca Chawner Research Theme Neuroscience & Mental Health Project Summary Download Summary Tackling eating disorders is of growing importance in society, with increasing numbers of children and young people referred to eating disorder services. This PhD project focuses…
The MEME project: Making Exercise interventions More Effective for depression and anxiety
Project Code MRCNMH25Br Wootton Research Theme Neuroscience & Mental Health Project Summary Download Summary Exercise has been repeatedly shown to improve symptoms of depression and anxiety. Therefore, prescribing exercise could be an effective alternative (or adjunct) to treatment for the…
Optical micro-structures and their application in next-generation brain-computer interface systems
Project Code MRCNMH25Br Whitcomb Research Theme Neuroscience & Mental Health Project Summary Download Summary Brain-computer interfacing (BCI) could fundamentally transform how humans interact with computers. Current uses include prosthetic limb control, but future use could involve transformative technologies ranging from…
Finding the missing link in memory networks: Deciphering cortical-thalamic communication pathways critical for successful memory
Project Code MRCNMH25Br Warburton Research Theme Neuroscience & Mental Health Project Summary Download Summary Our memories are stored in networks across the brain. Two regions, the lateral entorhinal cortex (LEC) and nucleus reuniens (NRe) are key parts of such a…