Project Code
MRCIIAR26Br Long
Project Type
Wet lab
Research Theme
Infection, Immunity, Antimicrobial Resistance and Repair
Project Summary Download
Summary
A paradigm shift is underway in type 1 diabetes (T1D) treatment. For over a century, T1D has been managed, but not cured, with insulin. Individuals in the earliest pre-clinical stages can be identified by measuring islet-autoantibodies, creating an opportunity to delay disease progression. This year marks the first use of immunotherapy in the NHS to postpone the onset of symptomatic T1D and insulin dependence. This project aims to further improve the identification of autoantibody-positive individuals most likely to benefit from immunotherapy, with the goal of transforming T1D care and ultimately preventing people with early stage T1D from ever requiring insulin.
Lead Supervisor
Dr Anna Long
Lead Supervisor Email
University Affiliation
Bristol