Project Code
MRCNMH26Br Mastitskaya
Project Type
Wet lab
Research Theme
Neuroscience and Mental Health
Project Summary Download
Summary
This PhD project will investigate how glucagon-like peptide-1 (GLP-1), a hormone central to metabolism, interacts with astrocytes – supportive “star-shaped” brain cells – to influence brain–heart communication. The project will employ cutting-edge techniques, including genetic targeting of specific brain cells, experimental models of heart attack, and advanced imaging, to explore how these pathways protect the heart. Conducted in collaboration with leading experts in Bristol and Exeter, the research will combine physiology, neuroscience, molecular biology, and data science. The findings aim to uncover new strategies to harness brain signals for heart protection and develop novel treatments for cardiovascular disease.
Lead Supervisor
Dr Svetlana Mastitskaya
Lead Supervisor Email
svetlana.mastitskaya@bristol.ac.uk
University Affiliation
Bristol