Neuronal Clues to Astrocytes: Uncovering Hidden Mechanisms in the Developing Brain

Project Code

MRCNMH26Ex Oguro-Ando

Project Type

Wet lab

Research Theme

Neuroscience and Mental Health

Project Summary Download

Summary

How do neuronal signals drive astrocyte-mediated changes in brain development? This project will investigate the underlying cellular and molecular mechanisms by which neuronal JAKMIP1 influences astrocytes, a key type of brain glial cell, and how this neuron-astrocyte communication is disrupted in autism and related developmental conditions. With training in RNA sequencing, microscopy, and brain cell analysis, you will uncover how interactions between brain cells shape development and behaviour. This is a unique opportunity to work at the interface of molecular neuroscience, cell biology, and neurodevelopment.

Lead Supervisor

Dr Asami Oguro-Ando

Lead Supervisor Email

A.Oguro-Ando@exeter.ac.uk

University Affiliation

Exeter