Project Code MRCNMH26Ba Mason Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Phosphorylation of the protein α-synuclein at serine 129 (pS129) is a defining feature of Parkinson’s disease and related conditions. This project will…
RNA-dependent regulation of the KAP1 chromatin protein controls neuronal stem cell function
Project Code MRCNMH26Ba Vance Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary The mammalian genome encodes hundreds of RNA binding proteins that associate with RNA using poorly defined modes of action. Mutations in these…
Bio-Computational Approaches to Understanding Transition to Psychosis
Project Code MRCNMH26Ba Walton Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary This project aims to advance our understanding of psychosis by identifying the biological mechanisms that underlie its diverse symptom profiles. Moving beyond…
The Experience and Impact of Psychedelic Therapy as Treatment for Mental Health Disorders in Women Survivors of Sexual Assault
Project Code MRCNMH26Ba Williamson Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Sexual assault (SA) often leads to mental health difficulties and, as standard treatments have poor response rates, many survivors suffer with long-term…
Transforming Obesity Care in Idiopathic Intracranial Hypertension: A Person-Centred, Multidisciplinary Approach
Project Code MRCNMH26Br Atan Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Idiopathic intracranial hypertension (IIH) is a serious neurological condition linked to obesity—but weight loss isn’t simple when disordered eating, trauma, and mental…
Can experiences in Virtual Reality change body perception and satisfaction, in people with and without eating disorders?
Project Code MRCNMH26Br Bould Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Current treatments for eating disorders only work for around two thirds of those affected, so it is vital to develop novel treatments.…
Understanding Combination Use of Tobacco, E-cigarettes, and Cannabis: Predicting Modifiable Risks and Treatment Pathways Using Machine Learning
Project Code MRCNMH26Br Burke Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Combination use of tobacco, e-cigarettes, and cannabis is increasingly common, particularly among young people, yet little is known about how these patterns…
Chrono-nutrition and Chrono-pharmacology: Investigating the Impact of Intermittent Fasting and Timed Pharmacological Treatments for Obesity Management
Project Code MRCNMH26Br Chrobok Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Most physiological processes, including feeding, follow circadian (~24h) cycles. In mammals, these rhythms are generated by endogenous ‘body clocks’ within the brain.…
Alternative mitochondrial destinations of PINK1 and its role in Parkinson’s Disease
Project Code MRCNMH26Br Collinson Project Type It is both a wet and a dry project. Research Theme Neuroscience and Mental Health Project Summary Download Summary Mitochondria are vital for energy production, cell function and homeostasis, and thereby health. This project…
Unlocking the secrets of fentanyl: exploring the anomalous pharmacology of fentanyl at the μ-opioid receptor
Project Code MRCNMH26Br Corey Project Type The project will be chiefly a dry project, but with the opportunity to work in the labs of the co-supervisors. It will be partly down to the student how much they do, however they…