Project Code
MRCNMH24Ex Piers
Research Theme
Neuroscience and Mental Health
Full Project Description
Please download the below document for a full project description and to see the full supervisory team.
Summary
Microglia are strongly linked to Alzheimer’s disease (AD), supported by significant cell-type specific genetic association. However, there is a substantial gap in our understanding of how genetic variation affect microglial response to pathology. This project will use culture models to uncover the mechanisms associated with microglial activation states using a multidisciplinary approach including microscopy, electrophysiology, epigenetics, and bioinformatics.
Lead Supervisor
Dr Thomas Piers
Lead Supervisor Email
t.piers@exeter.ac.uk
University Affiliation
Exeter