Project Code
MRCIIAR25Ca Serpi
Research Theme
Infection, Immunity, Antimicrobial Resistance and Repair
Project Summary Download
Summary
While antibiotics have revolutionised the landscape of medicine saving millions of lives, their misuse has also resulted in the rise of “Superbugs”, which are bacteria resistant to most of the standard antibiotics. Each year worldwide the number of people dying as infected with superbugs is alarming increasing. This project proposes to develop novel antimicrobials that target bacterial cell division, a crucial step for bacterial replication and survival. We will combine our expertise in medicinal chemistry and microbiology to design molecules that, acting like “Trojan horses”, cross the bacterial cell envelope and once inside become toxic and kill the bacteria.
Lead Supervisor
Dr Michaela Serpi
Lead Supervisor Email
serpim5@cardiff.ac.uk
University Affiliation
Cardiff