Exploring the role of hyaluronan in cognition across the lifespan

Project Code

MRCNMH25Br Mifsud

Research Theme

Neuroscience & Mental Health

Project Summary Download

Summary

Hyaluronan (HA) is a structural component found in the spaces between the cells. HA is involved in a range of physiological functions that depend on the length of HA present. HA plays a significant role in cognition, the ability to acquire and use knowledge productively, but the cellular/molecular mechanisms behind this association remain ill-defined. Understanding these mechanisms is important because cognitive decline is associated with poor health/wellbeing, with age being a major risk factor. This project will deliver training in highly desirable experimental skills, linking fundamental mechanistic studies in vivo with molecular epidemiological studies of human cohorts. 

Lead Supervisor

Dr Karen Mifsud

Lead Supervisor Email

K.Mifsud@bristol.ac.uk 

University Affiliation

Bristol