Project Code MRCNMH24Ca McNabb Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Aberrant brain structure and function are implicated in the…
AI and structure based drug discovery of chaperones for misfolded lysosomal enzymes involved in neurodegenerative disease
Project Code MRCNMH24Ca Lloyd-Evans Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary A major risk gene for Parkinson disease encodes a…
What goes up must come down? Using digital technology to understand the dynamic nature of mood in bipolar disorder
Project Code MRCNMH24Ca Lewis Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary People with bipolar disorder (BD) experience disabling episodes of…
Maternal anxiety and language delays in children – both outcomes of the same epigenetic alteration?
Project Code MRCNMH24Ca John Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Maternal depression and anxiety are highly common in pregnancy…
How does the schizophrenia candidate gene Sp4 influences transcription during neurodevelopment?
Project Code MRCNMH24Ca Isles Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Both common and rare variants in the gene encoding…
Untangling neurodegeneration and ageing components of neuroinflammatory disorders
Project Code MRCNMH24Ca Escott-Price Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Numerous genome-wide association studies (GWAS) show a strong, but…
Physical fatigue and the neural control of muscle activity in health and disease: Unravelling mechanisms and implications
Project Code MRCNMH24Ca DaviesJ Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Fatigue can be explained as the feeling that we…
Using a new translational in vivo model to understand the neurobiology underlying ADHD subtypes
Project Code MRCNMH24Ca Davies Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary In mice and humans loss-of-function of the steroid sulfatase…
Understanding neuronal dysfunction in Tuberous Sclerosis
Project Code MRCNMH24Br Wilkinson Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Mutations in the TSC1 gene lead to Tuberous Sclerosis…
Investigating the neurobiological mechanisms underlying apathy in Parkinson’s disease
Project Code MRCNMH24Br Robinson Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Apathy is a debilitating and highly prevalent symptom in…