Project Code NMH27Ca Cercignani Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary This PhD project explores how young children’s brain develops during the first five years of life and how this shapes thinking, language, and…
Finding the Earliest Signs of Psychosis: Studying Young People at High Genetic Risk
Project Code NMH27Ca Chawner Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Why do some young people develop psychosis while others do not? This project will investigate the developmental origins of psychosis in young…
Gene-diet interaction and psychiatric risk: A study based of FADS 2 and dietary polyunsaturated fatty acids (PUFAs)
Project Code NMH27Ca Harwood Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary Mental Health: nature or nurture? For psychiatric disorders the answer is both, but to explain how, we need to know the molecular mechanisms?…
Towards Precision Psychiatry: Early Detection and Intervention in Schizophrenia
Project Code NMH27Ca Heurich Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Schizophrenia affects around 1% of the population and remains one of the most challenging mental health disorders to predict and treat. Increasing…
Investigating placental function and fetal programming in Prader–Willi Syndrome
Project Code NMH27Ca Isles Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary By bringing together transcriptomics and cutting edge imaging, and dataanalysis techniques, this PhD project aims to examine how abnormalitiesin placental function leads…
Power Failure: Why Neurons Die in Huntington’s Disease
Project Code NMH27Ca Massey Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Huntington’s disease is an inherited brain disorder that causes progressive movement, cognitive and sleep problems, yet there is still no effective treatment.…
Unravelling the Physiological Drivers of Sleep-Dependent Glymphatic Flow in Alzheimer’s Disease using Advanced MRI
Project Code NMH27Ca Murphy Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary Poor sleep is linked to increased future dementia risk. The SleepBoost study is a £4.3m multi-centre investigation into this link and aims to…
Guarding the Brain’s Blueprint: Investigating UPF3B in DNA Repair, Autism, and ADHD
Project Code NMH27Ca Ngo Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Neurodevelopmental disorders (NDDs) like autism and ADHD affect millions, yet the underlying causes remain unclear. This PhD project investigates how mutations in…
Medication adherence in young people with first episode psychosis: a longitudinal mixed-methods biopsychosocial study of decision making
Project Code NMH27Ca Roberts Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Antipsychotic medication can reduce or resolve psychotic symptoms and help prevent relapse, but adherence remains challenging, particularly for young people with first…
From Multi-OMICs to mechanism: understanding the links between protein turnover and therapy resistance in glioblastoma stem cells
Project Code NMH27Ca Siebzehnrubl Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary How do glioblastoma stem cells evade therapy and drive tumour recurrence? This project will address this question by investigating how FGF2-FGFR1 signalling regulates…