Timing is Everything: Aligning Mealtime and Drug Treatment with the Body Clock to Fight Obesity

Project Code

NMH27Br Chrobok

Project Type

Wet lab

Research Theme

Neuroscience and Mental Health

Project Summary Download

Summary

Most physiological processes, including feeding, follow circadian (~24h) cycles. In mammals, these rhythms are generated by endogenous ‘body clocks’ within the brain. Dysfunction of these body clocks can contribute to obesity and other metabolic disorders. Our studies focus on a site in the brainstem that controls appetite which we have discovered also has robust circadian timekeeping. This project aims to understand how these daily rhythms in the brainstem satiety centre can be harnessed to formulate more effective strategies and treatments for tackling obesity.

Can the project be completed part time?

Yes

Lead Supervisor

Dr Lukasz Chrobok

Lead Supervisor Email

lukasz.chrobok@bristol.ac.uk

University Affiliation

University of Bristol

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