Project Code
MRCIIAR24Ca Peters
Research Theme
Infection, Immunity, Antimicrobial Resistance and Repair
Full Project Description
Please download the below document for a full project description and to see the full supervisory team.
Summary
Neuroinflammation is a prominent event Alzheimer’s disease (AD) pathogenesis driven by activation of microglia, the brains resident immune cells. To define how microglial gene expression is regulated in AD, this project utilises a state-of-the-art human stem cell culture model of AD coupled with epigenomic profiling and bioinformatic analysis. The role of prioritised genes will then be described through functional assays of important microglial processes.
Lead Supervisor
Dr Owen Peters
Lead Supervisor Email
PetersOM@cardiff.ac.uk
University Affiliation
Cardiff