Vascular morphology and haemodynamic risk of intracranial aneurysm in aortic coarctation

Project Code

CMD27Br Hart

Project Type

Dry lab

Research Theme

Cardiometabolic Disease

Project Summary Download

Summary

Aortic coarctation (CoA) is a common congenital heart disease, and even after successful repair, patients face elevated lifelong risk of hypertension, stroke, and intracranial aneurysm (IA). Why only a subset of patients develop these complications remains poorly understood, and no validated tools exist to identify who is at highest risk. This project will combine patient-specific 3D vascular reconstruction, machine learning, and computational fluid dynamics (CFD) to characterise the relationship between aortic and cerebrovascular morphology, blood flow patterns, and aneurysm risk in CoA. The aim is to generate the anatomical and haemodynamic evidence base needed for more targeted, personalised screening strategies.

Can the project be completed part time?

Yes

Lead Supervisor

Dr Emma Hart

Lead Supervisor Email

Emma.Hart@bristol.ac.uk

University Affiliation

University of Bristol

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