Project Code
NMH27Ex Mill
Project Type
Dry lab
Research Theme
Neuroscience and Mental Health
Project Summary Download
Summary
Why do males and females show different risks for brain disorders like schizophrenia, depression, autism and Alzheimer’s disease? This project explores how sex chromosomes shape gene expression and epigenetic regulation in the human brain across development and aging. Using cutting-edge multi-omic and single-cell datasets generated by our team and international collaborators, this bioinformatics project will investigate how the X and Y chromosomes drive molecular differences at the cellular level. You’ll also examine sex-specific differences in brains affected by neuropsychiatric and neurodegenerative disease. Join our dynamic research team to uncover the biological foundations of sex differences in brain health and disease.
Can the project be completed part time?
Yes
Lead Supervisor
Professor Jonathan Mill
Lead Supervisor Email
University Affiliation
University of Exeter
