Project Code MRCIIAR26Ca Parmeggiani Project Type The project combines dry- and wet-lab elements but aligns more closely with a wet-lab based project considering the costs needed to deliver the work. Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary…
Identification of novel antifungals: Synthesis, structure-activity correlation, and antifungal activity of novel molecular scaffolds from repurposable drugs
Project Code MRCIIAR26Ca Pertusati Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Fungal infections are a major threat to public health as they are becoming increasingly resistant to treatment. Only four classes…
Can Damage Associated Molecular Patterns be targeted to reduce susceptibility to infections in people with Chronic Kidney Disease?
Project Code MRCIIAR26Ca Raby Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary People with chronic kidney disease (CKD) are more vulnerable to infections, in part because their immune systems don’t function properly.…
Stop “Superbugs” to fight antimicrobial resistance
Project Code MRCIIAR26Ca Serpi Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary While antibiotics have revolutionised the landscape of medicine saving millions of lives, their misuse has also resulted in the rise…
From Survivor Blood to Curing Cancer
Project Code MRCIIAR26Ca Sewell Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary How do rare patients cure their own cancer?Some individuals with advanced cancers achieve complete remission, defying the odds without standard…
Immunological determinants of human cytomegalovirus control
Project Code MRCIIAR26Ca Stanton Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Humans exhibit variable outcomes when infected with identical pathogens for multiple reasons. We have discovered a new mechanism that may…
Unlocking the causes of eating disorders: investigating risk factors across development
Project Code MRCNMH25Ca Chawner Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Tackling eating disorders is of growing importance in society, with increasing numbers of children and young people referred to eating disorder services.…
A High-Efficiency and Sustainable Next-Generation Nanotherapeutic platform to Improve Astrocytoma Outcomes
Project Code MRCNMH26Ca Duc Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary In 2023, the Welsh and UK Government emphasised the urgent need for astrategic plan prioritising research in brain tumour therapy. Astrocytoma,comprising 1/3…
How ADHD affects curiosity and curiosity-based learning
Project Code MRCNMH26Ca Gruber Project Type The project will combine behavioural and neuroimaging studies (in particular, functional Magnetic Resonance Imaging, fMRI) in human participants. Research Theme Neuroscience and Mental Health Project Summary Download Summary This PhD project explores how curiosity…
SONIC-Glaucoma: Stimulation Of Neuroprotective & Immunomodulatory Cargos via Ultrasound in Glaucoma
Project Code MRCNMH26Ca Mead Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Glaucoma causes progressive retinal ganglion cell (RGC) loss and remains without effective neuroprotective therapy. While platelet-derived growth factor (PDGF) and brain-derived neurotrophic…