What goes up must come down? Using digital technology to understand the dynamic nature of mood in bipolar disorder

Project Code MRCNMH24Ca Lewis Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary People with bipolar disorder (BD) experience disabling episodes of…

Maternal anxiety and language delays in children – both outcomes of the same epigenetic alteration?

Project Code MRCNMH24Ca John Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Maternal depression and anxiety are highly common in pregnancy…

How does the schizophrenia candidate gene Sp4 influences transcription during neurodevelopment?

Project Code MRCNMH24Ca Isles Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Both common and rare variants in the gene encoding…

Untangling neurodegeneration and ageing components of neuroinflammatory disorders

Project Code MRCNMH24Ca Escott-Price Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Numerous genome-wide association studies (GWAS) show a strong, but…

Physical fatigue and the neural control of muscle activity in health and disease: Unravelling mechanisms and implications

Project Code MRCNMH24Ca DaviesJ Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Fatigue can be explained as the feeling that we…

Using a new translational in vivo model to understand the neurobiology underlying ADHD subtypes

Project Code MRCNMH24Ca Davies Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary In mice and humans loss-of-function of the steroid sulfatase…

Enhancing Immunological Control of SARS-CoV-2

Project Code MRCIIAR24Ca Stanton Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Neutralizing antibodies are key to preventing transmission…

Once bitten, twice shy: the impact of helminth infection on viral immunity

Project Code MRCIIAR24Ca Smith Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Although studies suggest that soil-transmitted helminth (STH)-infections…

Fighting antimicrobial resistance by stopping bacterial cell division

Project Code MRCIIAR24Ca Serpi Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary The continuing rise of antimicrobial resistance has…

Epigenetic regulation of microglial gene expression in Alzheimer’s disease

Project Code MRCIIAR24Ca Peters Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Neuroinflammation is a prominent event Alzheimer’s disease…