What drives the pain? Exploring the peripheral component in models of central sensitisation

Project Code NMH27Br Dunham Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Chronic primary pain affects 8 million UK adults, but we still do not understand what drives pain when there is no identifiable…

Developing brain-activity based non-invasive stimulation techniques for movement disorders

Project Code NMH27Br Fischer Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Parkinson’s disease and dystonia can severely affect movement, and existing treatments do not work well for everyone. This PhD project will develop…

Gatekeepers of GPCR Signalling: Degradation Pathways in Health and Disease

Project Code NMH27Br Grieve Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Neuropsychiatric disorders remain among the greatest challenges in medicine, yet we still lack a detailed understanding of how changes at the molecular…

Using human genomics, AI and fly disease modelling to study the relationship between sleep and Alzheimer’s disease

Project Code NMH27Br Hodge Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary With ageing your 24-hour clock (circadian rhythms) and sleep get weaker. These symptoms are more pronounced in Alzheimer’s with poor rhythms and…

Linking neuronal function to mental health: How genetic risk factors impair cognitive flexibility and neural plasticity in schizophrenia

Project Code NMH27Br Mellor Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Genetic risk factors for schizophrenia are clustered around genes that regulate synaptic function and adaptation, pointing to underlying biological processes whose disruption…

Quietly healing trauma: enhancing emotional processing during sleep with targeted memory reactivation

Project Code NMH27Br Purple Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Why do some people recover from trauma while others develop posttraumatic stress disorder (PTSD)? Sleep is known to play an essential role…

Social determinants of mental ill-health over the life course: longitudinal analysis of young people in the Philippines and UK.

Project Code NMH27Br Sharp Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary This interdisciplinary project provides training in global mental health and advanced epidemiological/statistical methods. Using data from two large cohorts in the Philippines…

Quantifying the impact of heatwaves on cognition, neuroanatomy, and mitochondrial function

Project Code NMH27Br Siviter Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Climate change is increasing the frequency and severity of heatwaves. In the UK, homes and essential infrastructure are not adequately prepared for…

Mapping the Developing Brain: Linking Structure and Function through Imaging

Project Code NMH27Ca Cercignani Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary This PhD project explores how young children’s brain develops during the first five years of life and how this shapes thinking, language, and…