Project Code IIAR27Ex Borah Slater Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Tuberculosis (TB) remains one of the world’s leading infectious killers, with the urgent need for new treatments. This exciting PhD…
Phage Power: Optimising Treatments for Bacterial Co-Infections
Project Code IIAR27Ex Castledine Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary As antibiotic resistance threatens modern medicine, phage therapy is emerging as a powerful new weapon against bacterial infections. These naturally occurring…
How does temperature shape selection for resistance across different antibiotics, strains, and species
Project Code IIAR27Ex Padfield Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Climate warming is linked to rising antimicrobial resistance (AMR), but the biological mechanisms remain poorly understood. This project asks how temperature…
Developing CRISPR-Cas antimicrobials to tackle antibiotic resistance spread in Klebsiella pneumoniae
Project Code IIAR27Ex van Houte Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Antimicrobial resistance (AMR) poses a major threat to human health, which is for a large part driven by plasmids (mobile…
How pathogens emerge: integrating large language models with comparative genomics to uncover the zoonotic potential of bacteria
Project Code IIAR27Ex Vos Project Type Dry lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Most emerging bacterial pathogens originate from animal hosts (are ‘zoonotic’), yet it is hard to predict which pathogen species are likely…
Bacterial pathogen evolution during antibiotic-phage combination treatment
Project Code IIAR27Ex Westra Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Antimicrobial resistance is a major threat to modern medicine, and bacteriophage therapy is a promising route to treat drug-resistant infections. Yet…
Synthetic heroin: understanding the dangers of nitazene drugs
Project Code NMH27Ba Bailey Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Drug-related deaths are now at the highest ever recorded in the UK, the majority involving opioid drugs. Currently, a new class of…
Understanding and improving the provision of clinical services for youth with disruptive behaviour disorders
Project Code NMH27Ba Fairchild Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary This PhD project will involve mapping mental health service provision for children and young people with disruptive behaviour disorders through a nationally…
Transdiagnostic mental health interventions for adversity affected youth
Project Code NMH27Ba Halligan Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Young people exposed to adversity are at risk of a range of mental health problems including anxiety, depression and conduct-related problems, making…
The brain-skin link in psychosis: uncovering shared biology and new treatment targets
Project Code NMH27Ba Lancaster Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Severe mental illnesses (e.g. schizophrenia/bipolar disorder) affect the whole body, not just the brain – and share genetic links with inflammatory conditions,…