Project Code IIAR27Ba Reis Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Bacterial infections affect millions of people worldwide. Current methodologies for bacterial identification and antibiotic susceptibility testing (AST) are time consuming or…
Reprogramming Antibodies: Novel Chemical Re-bridging to Overcome Immune Resistance in the Tumour Microenvironment
Project Code IIAR27Ba Watts Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Antibodies are powerful medicines that are used to guide the immune system to fight cancer. However, standard antibodies sometimes activate the…
Artificial intelligence to identify fungal susceptibility in the clinical diagnostic laboratory
Project Code IIAR27Br Dowsey Project Type Dry lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Fungal infections have become a major and growing global health crisis, causing an estimated 3.8 million deaths each year particularly from…
When immune memory becomes corrupted
Project Code IIAR27Br Koh Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Our immune system has a remarkable ability to “remember” infections and diseases, helping us respond more effectively to future threats. Exciting…
Deciphering Intramolecular Communication Networks to Identify New Antibiotic Targets in Multidrug-Resistant Bacteria
Project Code IIAR27Br Oliveira Project Type Other Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Bacteria are becoming resistant to many of our most important antibiotics, creating an urgent need for new treatments. This project will investigate…
Understanding beta-lactam antibiotic targets to improve melioidosis treatment
Project Code IIAR27Br Spencer Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Melioidosis, caused by the bacterium Burkholderia pseudomallei, is a severe, frequently fatal, tropical disease. Beta-lactam antibiotics are cornerstones of melioidosis treatment,…
Overcoming β-lactamase-mediated antibiotic resistance by combining biomolecular simulation and experiment
Project Code IIAR27Br Van der Kamp Project Type Other Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Antibiotic resistance threatens human health. β-lactamases cause resistance to β-lactams, the most widely used antibiotics. Class C β- lactamases are…
Understanding cellular ageing of protective immunity to inform vaccine design and T-cell therapies
Project Code IIAR27Ca Ladell Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary The risk of dying from infection is particularly high in the elderly and is related to ageing of the immune system.…
Receptor to Remedy: Rewiring adenovirus-host protein dynamics to engineer next-generation nanomedicines
Project Code IIAR27Ca Parker Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary How do viruses hijack our cells, and how can we turn this process to our advantage? This project will explore the…
Defining CD200 Function and the Therapeutic Potential of Targeting the CD200 immune checkpoint in Prostate Cancer
Project Code IIAR27Ca Pearson Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Prostate cancer remains a leading cause of cancer mortality, particularly in metastatic disease where treatment options are limited. This PhD project…