Project Code NMH27Ca Chawner Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Why do some young people develop psychosis while others do not? This project will investigate the developmental origins of psychosis in young…
Towards Precision Psychiatry: Early Detection and Intervention in Schizophrenia
Project Code NMH27Ca Heurich Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Schizophrenia affects around 1% of the population and remains one of the most challenging mental health disorders to predict and treat. Increasing…
Unravelling the Physiological Drivers of Sleep-Dependent Glymphatic Flow in Alzheimer’s Disease using Advanced MRI
Project Code NMH27Ca Murphy Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary Poor sleep is linked to increased future dementia risk. The SleepBoost study is a £4.3m multi-centre investigation into this link and aims to…
Medication adherence in young people with first episode psychosis: a longitudinal mixed-methods biopsychosocial study of decision making
Project Code NMH27Ca Roberts Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Antipsychotic medication can reduce or resolve psychotic symptoms and help prevent relapse, but adherence remains challenging, particularly for young people with first…
From Multi-OMICs to mechanism: understanding the links between protein turnover and therapy resistance in glioblastoma stem cells
Project Code NMH27Ca Siebzehnrubl Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary How do glioblastoma stem cells evade therapy and drive tumour recurrence? This project will address this question by investigating how FGF2-FGFR1 signalling regulates…
Chronic pain, sensory hypersensitivity and neurodiversity: why are they linked?
Project Code NMH27Ca Sumner Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Chronic pain conditions such as fibromyalgia, dysmenorrhea and back pain affect millions of people and severely disrupt daily life. An interesting but…
Pain as neurobiological surprise: Using human brain imaging and animal studies to advance new concepts in persistent pain.
Project Code NMH27Ca Tackley Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary We experience surprise when our best guess about the immediate future turns out to be wrong. This can be dangerous: it might mean…
Developing Blood Tests for the Early Detection of Neurodegeneration Following Traumatic Brain Injury
Project Code NMH27Ex Dempster Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Traumatic brain injury (TBI), including repetitive head impacts during contact sports, increases the risk of developing later-life neurodegenerative diseases such as chronic…
AI scientists for understanding dementia modifiable risk factors
Project Code NMH27Ex Dong Project Type Dry lab Research Theme Cardiometabolic Disease Infection, Immunity, Antimicrobial Resistance and Repair Neuroscience and Mental Health Population Health Science Project Summary Download Summary Early dementia prediction is an urgent problem to improve the clinical…
Air Pollution, Heat and Other Environmental Exposures in Relation to Cognitive Ageing: A Longitudinal Cohort Study
Project Code NMH27Ex HZhang Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary How do the environments we live in influence how our brains age? This PhD will use the PROTECT study, a large UK…