Project Code NMH27Ex Karl Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Many people who experience trauma go on to develop PTSD, and while talking therapies are effective, not everyone fully recovers. We examine…
From X to Y: Decoding Sex Chromosome Effects in the Human Brain
Project Code NMH27Ex Mill Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Why do males and females show different risks for brain disorders like schizophrenia, depression, autism and Alzheimer’s disease? This project explores how…
How Neurons Shape Astrocytes: Decoding Cell-to-Cell Communication in Brain Development
Project Code NMH27Ex Oguro-Ando Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary How do neurons instruct astrocytes to build the developing brain? This project explores how neuronal signals regulate astrocyte function and how this…
Discovery and functional testing of Alzheimer’s disease risk–resilience pathways in human iPSC microglia
Project Code NMH27Ex Piers Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Late onset Alzheimer’s disease (LOAD) risk is shaped by microglial genes, particularly the TREM2 signalling axis. The coding mutation TREM2 R47H increases…
Not Enough Money for Food and Struggling to Eat: Understanding the Connection Between Food Insecurity and Disordered Eating
Project Code NMH27Ex Turk Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary ARFID is an eating disorder where people avoid foods due to sensory sensitivities, fear of choking or vomiting, or low interest in…
Severe mental illness, inflammation and cardiometabolic health
Project Code NMH27Ex Tyrrell Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary This exciting PhD combines big data and genetics to understand the complex relationships between severe mental illness, inflammation, and obesity and other…
Investigating molecular mechanisms underlying resilience to dementia and age-related disorders: A multi-omic analysis of large human biobanks
Project Code NMH27Ex Walker Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Why do some people remain cognitively healthy despite being at high genetic risk of dementia? This project will use cutting-edge genetic and…
How sights become signals for learning
Project Code NMH27Ex YZhang Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary How does the brain discover that a sight predicts something important? This project will uncover the neural circuits that transform visual information…
The placenta and lifelong health of mothers and their offspring
Project Code PHS27Br AFraser Project Type Dry lab Research Theme Population Health Science Project Summary Download Summary The placenta is critical to a healthy pregnancy yet is often described as the least understood human organ. This project will investigate the…
What is behind the upsurge of colorectal cancer incidence among young adults?
Project Code PHS27Br Corbin Project Type Dry lab Research Theme Population Health Science Project Summary Download Summary Colorectal (bowel) cancer (CRC) is the third most diagnosed cancer and the second leading cause of cancer death globally. Whilst overall CRC incidence…